No. Although Minnesota defines hemp in the same way as the federal Farm Bill and legalizes Delta-8 THC and Delta-9 THC, THC-O is prohibited. Hence, it is illegal to sell or use THC-O in Minnesota.
THC-O, also called THC-O acetate, is a synthetic cannabinoid. While certain cannabinoids like CBG, CBD, and CBN may be derived from the hemp plant naturally, THC-O is not found naturally in hemp plants. Instead, THC-O is synthesized with acetic anhydride. Acetic anhydride is a highly flammable liquid commonly used to make fibers, plastics, dyes, pharmaceuticals, and explosives. The process of making THC-O starts with extracting Delta-8 THC from the hemp plant. Delta-8 THC molecules bind to acetic anhydride molecules to form THC-O which appears like a viscous brown liquid, like motor oil.
There is little scientific research on the effects of THC-O. However, anecdotal reports suggest it produces stronger psychedelic effects than other cannabinoids. Some commonly reported positive effects of THC-O include pain relief, anxiety relief, and appetite stimulation. Many users have also reported that side effects such as hallucinations, dizziness, seizures, nausea and vomiting, sedation, muscle weakness, and paranoia, outweigh the positive effects. THC-O is available in the form of vapes, edibles, oils, and tinctures.
The DEA has recently addressed inquiries from cannabis attorney Rod Kight regarding the legality of Delta-8 THC-O and Delta-9 THC-O. Controversies had trailed the legal status of THC-O due to arguments concerning the nature of the cannabinoid compared to some hemp other derivatives. Note that the Farm Bill legalized all derivatives of hemp in 2018, provided they contain no more than 0.3% Delta-9 THC.
According to the DEA's legal interpretation, THC-O does not meet the Farm Bill's hemp definition because hemp plants do not naturally produce this cannabinoid. Consequently, THC-O is classified under the DEA's Controlled Substances Act definitions. In the DEA’s response letter to Rod Kight, the DEA reaffirmed that all forms of tetrahydrocannabinols (THCs) are considered Schedule I controlled substances. This includes naturally occurring or synthetically produced THC compounds, along with their isomers and derivatives.
The DEA elaborated by declaring that Delta-9 THC-O and Delta-8 THC-O are tetrahydrocannabinols with chemical structures and pharmacological activities akin to those found in the cannabis plant. Therefore, Delta-9 THC-O and Delta-8 THC-O meet the definition of 'tetrahydrocannabinols,' and they, along with products containing Delta-9 THC-O and Delta-8 THC-O, are subject to control under Schedule I by 21 U.S.C. § 812(c), and 21 CFR § 1308.11(d)".
When you consume THC-O, it is absorbed into various body tissues or metabolized by the liver into 11-hydroxy-THC. While about 20% of the compound may leave the body through urine and 65% through feces, the rest is stored in the body. Among chronic THC-O users, THC metabolites build up in fatty tissues faster than they can be eliminated. Hence, THC can also show up on a drug test several weeks after use.
Like many drugs, the duration that THC-O metabolites can remain in a person's system varies with respect to other factors, such as:
Yes. Standard drug tests typically focus on detecting THC metabolites rather than specific THC compounds. Since THC-O undergoes metabolic processes similar to other THC cannabinoids, drug tests will return positive for THC use if you have consumed THC-O products recently. However, the test result may also vary depending on the type of drug test employed. Typical drug detention windows are shown below:
Delta-8 THC is a cannabinoid found in trace amounts in hemp plants. Unlike THC-O, it occurs naturally in cannabis plants but may also be synthesized from the more popular Delta-9 THC. Delta-8 THC and THC-O differ in the following ways:
Delta-8 THC has undergone more scientific research than THC-O, leading to a better understanding of its effects and safety profile. However, research continues on THC-O, requiring further investigation into its long-term effects and potential health risks. Note that individual factors, such as body composition, metabolism, and prior experiences with cannabinoids, may mean that the effects experienced by users may vary significantly between individuals based on factors.
Delta-9 THC is the most common form of THC and is well known for its psychoactive effects. The high feeling experienced by marijuana users when consuming cannabis is due to Delta-9 THC. However, despite sharing the "THC" name, there are certain differences between Delta-9 THC and THC-O, such as: